The remainder of this cover page shall be filled out for a reporting person’s initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter disclosures provided in a prior cover page.

  NAME OF REPORTING PERSON

  AI Life Sciences Investments LLC

  CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)

  (a)  ☐        (b)  ☐

  SEC USE ONLY:

  CITIZENSHIP OR PLACE OF ORGANIZATION:

  State of Delaware     

NUMBER OF

SHARES

  BENEFICIALLY  

BY

OWNED BY

EACH

REPORTING

PERSON

WITH

  SOLE VOTING POWER:

  0     

  SHARED VOTING POWER:

  2,888,200     

  SOLE DISPOSITIVE POWER:

  0     

  SHARED DISPOSITIVE POWER:

  3,028,742     

  AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON:

  3,028,742     

  CHECK IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES (SEE INSTRUCTIONS):

  ☐

  PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9):

  9.9%⁽¹⁾     

  TYPE OF REPORTING PERSON (SEE INSTRUCTIONS):

  OO (Limited Liability Company)     

Based on 30,177,203 outstanding shares of Common Stock as of February 4, 2020, as reported in the Issuer’s prospectus supplement dated January 31, 2020, and after giving effect to the February 4, 2020 purchase of 1,000,000 shares and pre-funded warrants to purchase up to 250,000 shares of the Issuer’s Common Stock.

  NAME OF REPORTING PERSON

  Access Industries Holdings LLC

  CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)

  (a)  ☐        (b)  ☐

  SEC USE ONLY:

  CITIZENSHIP OR PLACE OF ORGANIZATION:

  State of Delaware     

NUMBER OF

SHARES

  BENEFICIALLY  

BY

OWNED BY

EACH

REPORTING

PERSON

WITH

  SOLE VOTING POWER:

  0     

  SHARED VOTING POWER:

  2,888,200     

  SOLE DISPOSITIVE POWER:

  0     

  SHARED DISPOSITIVE POWER:

  3,028,742     

  AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON:

  3,028,742     

  CHECK IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES (SEE INSTRUCTIONS):

  ☐

  PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9):

  9.9%⁽¹⁾     

  TYPE OF REPORTING PERSON (SEE INSTRUCTIONS):

  OO (Limited Liability Company)     

Based on 30,177,203 outstanding shares of Common Stock as of February 4, 2020, as reported in the Issuer’s prospectus supplement dated January 31, 2020, and after giving effect to the February 4, 2020 purchase of 1,000,000 shares and pre-funded warrants to purchase up to 250,000 shares of the Issuer’s Common Stock.

  NAME OF REPORTING PERSON

  Access Industries Management, LLC

  CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)

  (a)  ☐        (b)  ☐

  SEC USE ONLY:

  CITIZENSHIP OR PLACE OF ORGANIZATION:

  State of Delaware     

NUMBER OF

SHARES

  BENEFICIALLY  

BY

OWNED BY

EACH

REPORTING

PERSON

WITH

  SOLE VOTING POWER:

  0     

  SHARED VOTING POWER:

  2,888,200     

  SOLE DISPOSITIVE POWER:

  0     

  SHARED DISPOSITIVE POWER:

  3,028,742     

  AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON:

  3,028,742     

  CHECK IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES (SEE INSTRUCTIONS):

  ☐

  PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9):

  9.9%⁽¹⁾     

  TYPE OF REPORTING PERSON (SEE INSTRUCTIONS):

  OO (Limited Liability Company)     

Based on 30,177,203 outstanding shares of Common Stock as of February 4, 2020, as reported in the Issuer’s prospectus supplement dated January 31, 2020, and after giving effect to the February 4, 2020 purchase of 1,000,000 shares and pre-funded warrants to purchase up to 250,000 shares of the Issuer’s Common Stock.

  NAME OF REPORTING PERSON

  Len Blavatnik

  CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)

  (a)  ☐        (b)  ☐

  SEC USE ONLY:

  CITIZENSHIP OR PLACE OF ORGANIZATION:

  United States of America

NUMBER OF

SHARES

  BENEFICIALLY  

BY

OWNED BY

EACH

REPORTING

PERSON

WITH

  SOLE VOTING POWER:

  0     

  SHARED VOTING POWER:

  2,888,200     

  SOLE DISPOSITIVE POWER:

  0     

  SHARED DISPOSITIVE POWER:

  3,028,742     

  AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON:

  3,028,742     

  CHECK IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES (SEE INSTRUCTIONS):

  ☐

  PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9):

  9.9%⁽¹⁾     

  TYPE OF REPORTING PERSON (SEE INSTRUCTIONS):

  IN

Based on 30,177,203 outstanding shares of Common Stock as of February 4, 2020, as reported in the Issuer’s prospectus supplement dated January 31, 2020, and after giving effect to the February 4, 2020 purchase of 1,000,000 shares and pre-funded warrants to purchase up to 250,000 shares of the Issuer’s Common Stock.

Name of Issuer:

Address of Issuer’s Principal Executive Offices:

Name of Person Filing:

Address of Principal Business Office or, if none, Residence:

Citizenship:

Title of Class of Securities:

CUSIP Number:

If this statement is filed pursuant to §§ 240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:

Ownership.

Amount

beneficially

owned

Percent

of class:

Sole
power to
dispose or
to direct
the
disposition

of:

Shared

power to

dispose or

to direct

the

disposition

of:

AI Life Sciences Investments LLC

Access Industries Holdings LLC

Access Industries Management, LLC

Len Blavatnik

Ownership of Five Percent or Less of a Class.

Ownership of More than Five Percent on Behalf of Another Person.

Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the parent Holding Company or Control Person.

Identification and Classification of Members of the Group.

Notice of Dissolution of Group.

Certifications.

/s/ Alejandro Moreno

Alejandro Moreno / Executive Vice President

/s/ Alejandro Moreno

Alejandro Moreno / Executive Vice President

/s/ Alejandro Moreno

Alejandro Moreno / Executive Vice President

*

Len Blavatnik

The undersigned, by signing his name hereto, executes this Schedule 13G pursuant to the Power of Attorney executed on behalf of Mr. Blavatnik (as filed with the Securities and Exchange Commission on February 13, 2015).

/s/ Alejandro Moreno

/s/ Alejandro Moreno

Alejandro Moreno / Executive Vice President

/s/ Alejandro Moreno

Alejandro Moreno / Executive Vice President

/s/ Alejandro Moreno

Alejandro Moreno / Executive Vice President

*

Len Blavatnik

The undersigned, by signing his name hereto, executes this Joint Filing Agreement pursuant to the Power of Attorney executed on behalf of Mr. Blavatnik (as filed with the Securities and Exchange Commission on February 13, 2015).

/s/ Alejandro Moreno