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SC 13G

 

 

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

WASHINGTON, D.C. 20549

 

 

SCHEDULE 13G

UNDER THE SECURITIES EXCHANGE ACT OF 1934

(Amendment No.     )*

 

 

Syndax Pharmaceuticals, Inc.

(Name of Issuer)

Common Stock

(Title of Class of Securities)

87164F105

(CUSIP Number)

December 31, 2016

(Date of Event Which Requires Filing of This Statement)

 

 

Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

☐ Rule 13d-1(b)

☐ Rule 13d-1(c)

☒ Rule 13d-1(d)

 

* The remainder of this cover page shall be filled out for a reporting person’s initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter the disclosures provided in a prior cover page.

The information required in the remainder of this cover page shall not be deemed to be “filed” for the purpose of Section 18 of the Securities Exchange Act of 1934 (“Act”) or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).

 

 

 

 

Page 1 of 14

CUSIP No. 87164F105

 

  1.   

Name of Reporting Persons

 

MPM BioVentures IV-QP, L.P.

  2.  

Check the Appropriate Box if a Member of a Group (See Instructions)

(a)  ☐        (b)  ☒

 

  3.  

SEC USE ONLY

 

  4.  

Citizenship or Place of Organization

 

Delaware

Number of

Shares

Beneficially

Owned by

Each

Reporting

Person

With:

    5.    

Sole Voting Power

 

1,806,759

   6.   

Shared Voting Power

 

0

   7.   

Sole Dispositive Power

 

1,806,759

   8.   

Shared Dispositive Power

 

0

  9.  

Aggregate Amount Beneficially Owned by Each Reporting Person

 

1,806,759

10.  

Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions)

 

☐

11.  

Percent of Class Represented by Amount in Row (9)

 

9.9%

12.  

Type of Reporting Person (See Instructions)

 

PN

 

 

Page 2 of 14

CUSIP No. 87164F105

 

  1.   

Name of Reporting Persons

 

MPM BioVentures IV GmbH & Co. Beteiligungs KG

  2.  

Check the Appropriate Box if a Member of a Group (See Instructions)

(a)  ☐        (b)  ☒

 

  3.  

SEC USE ONLY

 

  4.  

Citizenship or Place of Organization

 

Germany

Number of

Shares

Beneficially

Owned by

Each

Reporting

Person

With:

    5.    

Sole Voting Power

 

69,600

   6.   

Shared Voting Power

 

0

   7.   

Sole Dispositive Power

 

69,600

   8.   

Shared Dispositive Power

 

0

  9.  

Aggregate Amount Beneficially Owned by Each Reporting Person

 

69,600

10.  

Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions)

 

☐

11.  

Percent of Class Represented by Amount in Row (9)

 

0.4%

12.  

Type of Reporting Person (See Instructions)

 

PN

 

 

Page 3 of 14

CUSIP No. 87164F105

 

  1.   

Name of Reporting Persons

 

MPM Asset Management Investors BV4 LLC

  2.  

Check the Appropriate Box if a Member of a Group (See Instructions)

(a)  ☐        (b)  ☒

 

  3.  

SEC USE ONLY

 

  4.  

Citizenship or Place of Organization

 

Delaware

Number of

Shares

Beneficially

Owned by

Each

Reporting

Person

With:

    5.    

Sole Voting Power

 

51,369

   6.   

Shared Voting Power

 

0

   7.   

Sole Dispositive Power

 

51,369

   8.   

Shared Dispositive Power

 

0

  9.  

Aggregate Amount Beneficially Owned by Each Reporting Person

 

51,369

10.  

Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions)

 

☐

11.  

Percent of Class Represented by Amount in Row (9)

 

0.3%

12.  

Type of Reporting Person (See Instructions)

 

OO

 

 

Page 4 of 14

CUSIP No. 87164F105

 

  1.   

Name of Reporting Persons

 

MPM BioVentures IV Strategic Fund, L.P.

  2.  

Check the Appropriate Box if a Member of a Group (See Instructions)

(a)  ☐        (b)  ☒

 

  3.  

SEC USE ONLY

 

  4.  

Citizenship or Place of Organization

 

Delaware

Number of

Shares

Beneficially

Owned by

Each

Reporting

Person

With:

    5.    

Sole Voting Power

 

240,963

   6.   

Shared Voting Power

 

0

   7.   

Sole Dispositive Power

 

240,963

   8.   

Shared Dispositive Power

 

0

  9.  

Aggregate Amount Beneficially Owned by Each Reporting Person

 

240,963

10.  

Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions)

 

☐

11.  

Percent of Class Represented by Amount in Row (9)

 

1.3%

12.  

Type of Reporting Person (See Instructions)

 

PN

 

 

Page 5 of 14

CUSIP No. 87164F105

 

  1.   

Name of Reporting Persons

 

MPM BioVentures IV GP LLC

  2.  

Check the Appropriate Box if a Member of a Group (See Instructions)

(a)  ☐        (b)  ☒

 

  3.  

SEC USE ONLY

 

  4.  

Citizenship or Place of Organization

 

Delaware

Number of

Shares

Beneficially

Owned by

Each

Reporting

Person

With:

    5.    

Sole Voting Power

 

0

   6.   

Shared Voting Power

 

2,117,322*

   7.   

Sole Dispositive Power

 

0

   8.   

Shared Dispositive Power

 

2,117,322*

  9.  

Aggregate Amount Beneficially Owned by Each Reporting Person

 

2,117,322*

10.  

Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions)

 

☐

11.  

Percent of Class Represented by Amount in Row (9)

 

11.6%

12.  

Type of Reporting Person (See Instructions)

 

PN

 

* Consists of 1,806,759 shares of Common Stock held by MPM BioVentures IV-QP, L.P. (“BV IV QP”), 69,600 shares of Common held by MPM BioVentures IV GmbH & Co. Beteiligungs KG (“BV KG”) and 240,963 shares of Common by MPM BioVentures IV Strategic Fund, L.P. (“BV SF”). The Reporting Person is the direct general partner of BV IV QP, BV KG and BV SF.

 

Page 6 of 14

CUSIP No. 87164F105

 

  1.   

Name of Reporting Persons

 

MPM BioVentures IV LLC

  2.  

Check the Appropriate Box if a Member of a Group (See Instructions)

(a)  ☐        (b)  ☒

 

  3.  

SEC USE ONLY

 

  4.  

Citizenship or Place of Organization

 

Delaware

Number of

Shares

Beneficially

Owned by

Each

Reporting

Person

With:

    5.    

Sole Voting Power

 

0

   6.   

Shared Voting Power

 

2,168,691*

   7.   

Sole Dispositive Power

 

0

   8.   

Shared Dispositive Power

 

2,168,691*

  9.  

Aggregate Amount Beneficially Owned by Each Reporting Person

 

2,168,691*

10.  

Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions)

 

☐

11.  

Percent of Class Represented by Amount in Row (9)

 

11.9%

12.  

Type of Reporting Person (See Instructions)

 

OO

 

* Consists of 1,806,759 shares of Common Stock held by BV IV QP, 69,600 shares of Common held by BV KG, 240,963 shares of Common Stock held by BV SF and 51,369 shares of Common Stock held by MPM Asset Management Investors BV4 LLC (“AM BV4”). The Reporting Person is the indirect general partner of BV IV QP, BV KG and BV SF and the manager of AM BV4.

 

Page 7 of 14

CUSIP No. 87164F105

 

  1.   

Name of Reporting Persons

 

Luke Evnin

  2.  

Check the Appropriate Box if a Member of a Group (See Instructions)

(a)  ☐        (b)  ☒

 

  3.  

SEC USE ONLY

 

  4.  

Citizenship or Place of Organization

 

United States

Number of

Shares

Beneficially

Owned by

Each

Reporting

Person

With:

    5.    

Sole Voting Power

 

15,610*

   6.   

Shared Voting Power

 

2,168,691**

   7.   

Sole Dispositive Power

 

15,610*

   8.   

Shared Dispositive Power

 

2,168,691**

  9.  

Aggregate Amount Beneficially Owned by Each Reporting Person

 

2,184,301* **

10.  

Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions)

 

☐

11.  

Percent of Class Represented by Amount in Row (9)

 

12.0%

12.  

Type of Reporting Person (See Instructions)

 

IN

 

* Consists of shares of Common Stock issuable pursuant to options which are exercisable within 60 days of December 31, 2016.
** Consists of 1,806,759 shares of Common Stock held by BV IV QP, 69,600 shares of Common held by BV KG, 240,963 shares of Common Stock held by BV SF and 51,369 shares of Common Stock held by AM BV4. The Reporting Person is the indirect general partner of BV IV QP, BV KG and BV SF and the manager of AM BV4. MPM IV GP and MPM IV LLC are the direct and indirect general partners of BV IV QP, BV KG and BV SF and MPM IV LLC is the manager of AM BV4. The Reporting Person is a member of MPM IV LLC.

 

Page 8 of 14

CUSIP No. 87164F105

 

  1.   

Name of Reporting Persons

 

Ansbert Gadicke

  2.  

Check the Appropriate Box if a Member of a Group (See Instructions)

(a)  ☐        (b)  ☒

 

  3.  

SEC USE ONLY

 

  4.  

Citizenship or Place of Organization

 

United States

Number of

Shares

Beneficially

Owned by

Each

Reporting

Person

With:

    5.    

Sole Voting Power

 

0

   6.   

Shared Voting Power

 

2,168,691*

   7.   

Sole Dispositive Power

 

0

   8.   

Shared Dispositive Power

 

2,168,691*

  9.  

Aggregate Amount Beneficially Owned by Each Reporting Person

 

2,168,691*

10.  

Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions)

 

☐

11.  

Percent of Class Represented by Amount in Row (9)

 

11.9%

12.  

Type of Reporting Person (See Instructions)

 

IN

 

* Consists of 1,806,759 shares of Common Stock held by BV IV QP, 69,600 shares of Common held by BV KG, 240,963 shares of Common Stock held by BV SF and 51,369 shares of Common Stock held by AM BV4. The Reporting Person is the indirect general partner of BV IV QP, BV KG and BV SF and the manager of AM BV4. MPM IV GP and MPM IV LLC are the direct and indirect general partners of BV IV QP, BV KG and BV SF and MPM IV LLC is the manager of AM BV4. The Reporting Person is a member of MPM IV LLC.

 

Page 9 of 14

CUSIP No. 87164F105

 

  1.   

Name of Reporting Persons

 

Todd Foley

  2.  

Check the Appropriate Box if a Member of a Group (See Instructions)

(a)  ☐        (b)  ☒

 

  3.  

SEC USE ONLY

 

  4.  

Citizenship or Place of Organization

 

United States

Number of

Shares

Beneficially

Owned by

Each

Reporting

Person

With:

    5.    

Sole Voting Power

 

0

   6.   

Shared Voting Power

 

2,168,691*

   7.   

Sole Dispositive Power

 

0

   8.   

Shared Dispositive Power

 

2,168,691*

  9.  

Aggregate Amount Beneficially Owned by Each Reporting Person

 

2,168,691*

10.  

Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions)

 

☐

11.  

Percent of Class Represented by Amount in Row (9)

 

11.9%

12.  

Type of Reporting Person (See Instructions)

 

IN

 

* Consists of 1,806,759 shares of Common Stock held by BV IV QP, 69,600 shares of Common held by BV KG, 240,963 shares of Common Stock held by BV SF and 51,369 shares of Common Stock held by AM BV4. The Reporting Person is the indirect general partner of BV IV QP, BV KG and BV SF and the manager of AM BV4. MPM IV GP and MPM IV LLC are the direct and indirect general partners of BV IV QP, BV KG and BV SF and MPM IV LLC is the manager of AM BV4. The Reporting Person is a member of MPM IV LLC.

 

Page 10 of 14

Item 1.

 

  (a) Name of Issuer

Syndax Pharmaceuticals, Inc.

 

  (b) Address of Issuer’s Principal Executive Offices

400 Totten Pond Road, Suite 110

Waltham, MA 02451

Item 2.

 

  (a) Name of Person Filing

MPM BioVentures IV-QP, L.P.

MPM BioVentures IV GmbH & Co. Beteiligungs KG

MPM Asset Management Investors BV4 LLC

MPM BioVentures IV Strategic Fund, L.P.

MPM BioVentures IV GP LLC

MPM BioVentures IV LLC

Luke Evnin

Ansbert Gadicke

Todd Foley

 

  (b) Address of Principal Business Office or, if none, Residence

c/o MPM Capital LLC

450 Kendall Street

Cambridge, MA 02142

 

  (c) Citizenship

All entities were organized in Delaware except MPM BioVentures IV GmbH & Co. Beteiligungs KG, which was organized in Germany. The individuals are all United States citizens.

 

  (d) Title of Class of Securities

Common Stock

 

  (e) CUSIP Number

87164F105

 

Item 3. If this statement is filed pursuant to §§240.13d-1(b), or 240.13d-2(b) or (c), check whether the person filing is a:

Not applicable

 

Page 11 of 14

Item 4. Ownership

 

MPM Entity

    Shares
Held
Directly		      Sole Voting
Power		      Shared
Voting
Power		      Sole
Dispositive
Power		      Shared
Dispositive
Power		      Beneficial
Ownership		      Percentage
of Class		  

BV IV QP

      1,806,759         1,806,759         0         1,806,759         0         1,806,759         9.9 % 

BV KG

      69,600         69,600         0         69,600         0         69,600         0.4 % 

BV SF

      240,963         240,963         0         240,963         0         240,963         1.3 % 

AM BV4

      51,369         51,369         0         51,369         0         51,369         0.3 % 

BV IV GP(1)

      0         0         2,117,322         0         2,117,322         2,117,322         11.6 % 

BV IV LLC(2)

      0         0         2,168,691         0         2,168,691         2,168,691         11.9 % 

Luke Evnin(3)(4)

      0         15,610         2,168,691         15,610         2,168,691         2,184,301         12.0 % 

Ansbert Gadicke(3)

      0         0         2,168,691         0         2,168,691         2,168,691         11.9 % 

Todd Foley(3)

      0         0         2,168,691         0         2,168,691         2,168,691         11.9 % 

 

(1) Consists of 1,806,759 shares of Common Stock held by BV IV QP, 69,600 shares of Common Stock held by BV KG and 240,963 shares of Common held by BV SF. The Reporting Person is the direct general partner of BV IV QP and BV KG.
(2) Consists of 1,806,759 shares of Common Stock held by BV IV QP, 69,600 shares of Common Stock held by BV KG, 240,963 shares of Common held by BV SF and 51,369 shares of Common Stock held by AM BV4. The Reporting Person is the indirect general partner of BV IV QP and BV KG and the manager of AM BV4.
(3) Consists of 1,806,759 shares of Common Stock held by BV IV QP, 69,600 shares of Common Stock held by BV KG and 240,963 shares of Common held by BV SF. MPM IV GP and MPM IV LLC are the direct and indirect general partners of BV IV QP, BV KG and BV SF and MPM IV LLC is the manager of AM BV4. The Reporting Person is a member of MPM IV LLC.
(4) Consists of shares of Common Stock issuable pursuant to options which are exercisable within 60 days of December 31, 2016.

 

Item 5. Ownership of Five Percent or Less of a Class

If this statement is being filed to report the fact that as of the date hereof the reporting person has ceased to be the beneficial owner of more than five percent of the class of securities, check the following  ☐.

 

Item 6. Ownership of More than Five Percent on Behalf of Another Person

Not Applicable

 

Item 7. Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on By the Parent Holding Company or Control Person.

Not Applicable

 

Item 8. Identification and Classification of Members of the Group

Not Applicable

 

Item 9. Notice of Dissolution of a Group

Not Applicable

 

Item 10. Certification

Not Applicable

 

Page 12 of 14

SIGNATURE

After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

Dated: February 8, 2017

 

MPM BIOVENTURES IV-QP, L.P.       MPM BIOVENTURES IV GMBH & CO. BETEILIGUNGS KG  
By:  

MPM BioVentures IV GP LLC,

its General Partner

       By:  

MPM BioVentures IV GP LLC,

in its capacity as the Managing Limited Partner

  
By:  

MPM BioVentures IV LLC,

its Managing Member

       By:  

MPM BioVentures IV LLC,

its Managing Member

  
By:  

/s/ Luke Evnin

       By:  

/s/ Luke Evnin

  
  Name: Luke Evnin         Name: Luke Evnin  
  Title: Member         Title: Member  
MPM ASSET MANAGEMENT INVESTORS BV4 LLC       MPM BIOVENTURES IV STRATEGIC FUND, L.P.  
By:   MPM BioVentures IV LLC       By:   MPM BioVentures IV GP LLC,  
  its Manager         its General Partner  
By:  

/s/ Luke Evnin

       By:   MPM BioVentures IV LLC,  
  Name: Luke Evnin         its Managing Member  
  Title: Member          
        By:  

/s/ Luke Evnin

  
          Name: Luke Evnin  
          Title: Member  
MPM BIOVENTURES IV GP LLC       MPM BIOVENTURES IV LLC  
By:   MPM BioVentures IV LLC,       By:  

/s/ Luke Evnin

  
  its Managing Member       Name:   Luke Evnin  
        Title:   Member  
By:  

/s/ Luke Evnin

          
Name:   Luke Evnin          
Title:   Member          
By:  

/s/ Luke Evnin

       By:  

/s/ Ansbert Gadicke

  
  Name: Luke Evnin         Name: Ansbert Gadicke  
By:  

/s/ Todd Foley

          
  Name: Todd Foley          

EXHIBITS

 

A: Joint Filing Agreement

 

Page 13 of 14

EX-99.A

EXHIBIT A

JOINT FILING AGREEMENT

In accordance with Rule 13d-1(k) under the Securities Exchange Act of 1934, as amended, the undersigned agree to the joint filing on behalf of each of them of a statement on Schedule 13G (including amendments thereto) with respect to the Common Stock of Syndax Pharmaceuticals, Inc. and further agree that this agreement be included as an exhibit to such filing. Each party to the agreement expressly authorizes each other party to file on its behalf any and all amendments to such statement. Each party to this agreement agrees that this joint filing agreement may be signed in counterparts.

In evidence whereof, the undersigned have caused this Agreement to be executed on their behalf this 8th day of February, 2017.

 

MPM BIOVENTURES IV-QP, L.P.      MPM BIOVENTURES IV GMBH & CO. BETEILIGUNGS KG
By:   MPM BioVentures IV GP LLC,      By:   MPM BioVentures IV GP LLC,   
  its General Partner        in its capacity as the Managing Limited Partner   
By:   MPM BioVentures IV LLC,      By:   MPM BioVentures IV LLC,   
  its Managing Member        its Managing Member   
By:  

/s/ Luke Evnin

      By:  

/s/ Luke Evnin

   
  Name: Luke Evnin        Name: Luke Evnin   
  Title: Member        Title: Member   
MPM ASSET MANAGEMENT INVESTORS BV4 LLC      MPM BIOVENTURES IV STRATEGIC FUND, L.P.
By:   MPM BioVentures IV LLC      By:   MPM BioVentures IV GP LLC,   
  its Manager        its General Partner   
By:  

/s/ Luke Evnin

      By:   MPM BioVentures IV LLC,   
  Name: Luke Evnin        its Managing Member   
  Title: Member          
       By:  

/s/ Luke Evnin

   
         Name: Luke Evnin   
         Title: Member   
MPM BIOVENTURES IV GP LLC      MPM BIOVENTURES IV LLC
By:   MPM BioVentures IV LLC,      By:  

/s/ Luke Evnin

   
  its Managing Member      Name:   Luke Evnin   
       Title:   Member   
By:  

/s/ Luke Evnin

          
Name:   Luke Evnin          
Title:   Member          
By:  

/s/ Luke Evnin

      By:  

/s/ Ansbert Gadicke

   
  Name: Luke Evnin        Name: Ansbert Gadicke   
By:  

/s/ Todd Foley

          
  Name: Todd Foley